OsteoGen® Bioactive Resorbable Calcium Apatite Graft
crystalline osteoconductive bioactive and resorbable calcium apatite bone graft
Radiolucent on day of surgery – Radiopaque in 4-6 months
Calcium Phosphate based bone graft that is NOT a β-TCP and NOT a dense ceramic HA, nor is it a biphasic mixture of the two. OsteoGen has a unique Ca:P ratio that mimics the composition of human bone
Non-Ceramic highly porous crystals physicochemically similar to trabecular bone
* OsteoGen® has a unique
crystal cluster structure that is highly hydrophilic leading to the immediate
absorption of blood flow and cellular proliferation – a feature critical for
the initiation of bone formation and early angiogenesis
* OsteoGen® proven safe,
reliable and clinically effective for use with implants for over 30 years
Available in 3.0 gram (6.0cc), 1.5 gram (3.0cc) and 0.75 gram (1.5cc) vials
* Pack OsteoGen® very well into the
® Vials have 6 Years of Shelf Life
OsteoGen® Synthetic Bioactive Resorbable
crystals and crystal clusters in 300 to 400μ are osteoconductive, highly
hydrophilic, resorbable, synthetically-derived non-ceramic form of
hydroxylapatite, the major mineral component of bone and dental enamel.
OsteoGen®, [Ca5(PO4)3(OH)] is
used for the augmentation and repair in periodontal and oralmaxillofacial bone
OsteoGen® is a highly crystalline pure
material, comparable to natural bone by its physiochemical properties, with NO
α/β tricalcium phosphates, amorphous phases, or bone-inhibiting pyro-phosphates
found in ceramic HA which is devoid of the hydroxyl group.
manufacturing produces bone grafting crystals of nearly perfectly-formed
clusters bound to a single nucleus and relatively hexagonal-shaped crystals.
These clusters intertwine to each other for greater porosity to form a 360º
lattice mechanism for the host cell proliferation and integration.
OsteoGen® is an osteoconductive material
in that the highly porous crystalline clusters act as a slowly-resorbing matrix
permitting the infiltration of bone-forming cells and the subsequent deposition
of host bone.
non-ceramic crystal clusters are highly hydrophilic, allowing the material to
readily absorb medullary blood and migration or material loss is greatly
reduced by controlling excessive bleeding with gauze.
has been shown to meet and exceed ASTM standards and specifications. OsteoGen® bone graft by
dental x-ray will show as radiolucent the day of placement in defect sites.
Four to six months later, the defect site will be radiopaque depending on
vascularity, patient’s age and quantity of product delivered. In many animal
and clinical studies,
has been shown to control migration of connective tissue.
is simple and delivery is easily accomplished with conventional instrumentation
or syringe in a sandy consistency.
product well at defect site.
OsteoGen bioactive resorbable apatite mimics bone structure to help with bone regeneration during dental bone grafts. These calcium apatite bone-grafting crystals are hydrophilic, meaning they draw in blood to start the regrowth process. These crystals are also bioactive and resorbable, allowing them to react with the patient’s cells and slowly break down into non-harmful components that can be assimilated into the body, making them exceptionally useful when it comes to bone grafts for teeth. OsteoGen crystal clusters are radiolucent on the day of placement. Over time, their structure changes, making them radiopaque in four to six months after placement. This makes it easy to check bone growth, so you know when the area is ready to place an implant.